Yuan, Jun-Hui https://orcid.org/0000-0002-3808-7813
Higuchi, Yujiro
Ando, Masahiro https://orcid.org/0000-0002-6187-9042
Hashiguchi, Akihiro
Okamoto, Yuji
Hiramatsu, Yu
Yoshimura, Akiko
Kodama, Kento
Sakiyama, Yusuke
Mitsui, Jun https://orcid.org/0000-0001-7425-4765
Tsuji, Shoji https://orcid.org/0000-0001-5602-5686
Takashima, Hiroshi https://orcid.org/0000-0003-0989-6141
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP22K07495, JP22K07495, JP20K16604, JP22K07519, JP21K15702, JP23K06966, JP24K18708, JP22K15713, JP18H02742, JP21H02842)
Ministry of Health, Labour and Welfare (2016100002B)
Japan Agency for Medical Research and Development (201442014A, 201442071A)
Article History
Received: 8 September 2025
Revised: 2 October 2025
Accepted: 14 November 2025
First Online: 8 December 2025
Competing interests
: The authors declare no competing interests.