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Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape

Crossref DOI link: https://doi.org/10.1038/s12276-025-01532-y

Published Online: 2025-09-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lee, Soung-Hoon

Kang, Min-Jeong

Roh, Mi Ryung

Choi, Kang-Yell https://orcid.org/0000-0002-0952-3276
Funding

Funding for this research was provided by:

National Research Foundation of Korea (2022R1I1A1A01073599, RS-2022-NR075558)
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Text and Data Mining valid from 2025-09-01

Version of Record valid from 2025-09-01
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Article History

Received: 5 March 2025

Revised: 9 June 2025

Accepted: 16 June 2025

First Online: 1 September 2025

Competing interests

: The authors declare no competing interests.

: Ethical approval was obtained from the Ethics Committee of Qilu Hospital, Shandong University (3-2020-0366) or the Institutional Review Board of Severance Hospital, Yonsei University College of Medicine (09-013).

: The authors consent to publish the paper.

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