Shin, Ji Hye
Kim, Ji Young
Kim, Mi-Jeong
Kang, Yeeun
Lee, Ha-Jeong
Choi, Bongkum
Lee, Ji Su
Kwon, Dohee
Kim, Seo Hyun
Sung, Yoolim
Kim, Duk-Hwan
Shim, Jae-Hyuck https://orcid.org/0000-0002-4947-3293
Chun, Eunyoung
Lee, Ki-Young https://orcid.org/0000-0002-6722-1751
Funding for this research was provided by:
National Research Foundation of Korea (2023R1A2C1003762, RS-2023-00217189, 2021R1A2C1094478)
Article History
Received: 8 January 2025
Revised: 17 August 2025
Accepted: 24 August 2025
First Online: 18 November 2025
Competing interests
: The authors declare no competing interests.
: This study was conducted in accordance with the ethical principles stated in the Declaration of Helsinki. It was approved by the IRB (IRB no. 2010-07-204) of SMC (Seoul, Korea). Written informed consent to use pathological specimens for research was obtained from all patients before surgery. Lung tumor and matched normal specimens of enrolled patients were immediately frozen in liquid nitrogen and stored at −80 °C until use. Lung tumor tissues and matched lung normal tissues were verified by the Department of Laboratory Medicine and Pathology at SMC. The animal experimental procedures were approved by the IACUC of the Bioanalysis Center Animal Facility (IACUC no. 23-10-01) of GenNBio.