Cho, Jin Gu
Kim, Sung Wook
Yun, Eunsik
Yoon, Sumin
Choi, Jihea
Yeom, Dasol
Lee, Aram
Lee, Dawn
Jeong, Su Jin
Chang, Woochul https://orcid.org/0000-0001-7367-2586
Hwang, Woo Yeon
Kim, Youngsun
Na, Kiyong
Kim, Ki Hyung
Suh, Dong Soo
Choi, Kyung Un
Park, Jong Hoon https://orcid.org/0000-0002-8082-0214
Kim, Keun Il https://orcid.org/0000-0002-9680-6230
Yoo, Kyung Hyun https://orcid.org/0000-0003-2172-5564
Kwon, Byung Su
Kim, Jongmin https://orcid.org/0000-0002-6622-3368
Funding for this research was provided by:
National Research Foundation of Korea (NRF-RS-2023-00207857)
National Research Foundation of Korea (NRF-RS-2025-00515840)
National Research Foundation of Korea (RS-2024-00440682)
Korea Health Industry Development Institute (HI22C1654)
Korea Health Industry Development Institute (HI22C1654)
Article History
Received: 9 June 2025
Revised: 19 August 2025
Accepted: 28 August 2025
First Online: 5 December 2025
Competing interests
: The authors declare no competing interests.
: All authors have provided consent for the publication of the manuscript.
: All study participants provided informed consent via signed forms, and the study design was approved by the Institutional Review Board of Pusan National University Hospital (IRB-2001-010-087). The animal experiments were conducted in accordance with the regulations of Pusan National University Hospital, and all procedures were performed in accordance with the policies of the Institutional Animal Care and Use Committee of Pusan National University of Korea (PNUH-2017-110).