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Drug-induced gastrointestinal toxicity and barrier integrity: cytoskeleton-mediated impairment in a clinically relevant human intestinal epithelium model

Crossref DOI link: https://doi.org/10.1038/s12276-025-01635-6

Published Online: 2026-02-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yu, Won Dong

Lee, Sugi

Cho, Hyun-Soo https://orcid.org/0000-0002-8242-9390
Kwon, Ohman https://orcid.org/0000-0002-4744-5360
Lim, Jung Hwa

Jung, Cho-Rok

Jang, Byunghyun

Lee, Kyung Jin

Yoo, Jongman

Kim, Dae-Soo https://orcid.org/0000-0002-4999-1613
Lee, Hana https://orcid.org/0000-0001-7782-5711
Son, Mi-Young https://orcid.org/0000-0001-7590-8812
Funding

Funding for this research was provided by:

Ministry of Food and Drug Safety (22213MFDS386)

Ministry of Science, ICT and Future Planning (NRF-2018M3A9H3023077)

Korea Research Institute of Bioscience and Biotechnology (KGM4722533)

Korea Research Institute of Bioscience and Biotechnology (KGM1062511)
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Text and Data Mining valid from 2026-02-12

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Article History

Received: 13 August 2025

Revised: 5 November 2025

Accepted: 12 November 2025

First Online: 12 February 2026

Competing interests

: The authors declare no competing interests.

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