Bae, Jinhee
Kim, Sung Hoon
Jung, Sun A
Frankiv, Nazarii
Jin, Hyunjeong
Hwang, Eun Mi
Kim, Young-Min
Lee, Sangjoon
Im, Heh-In https://orcid.org/0000-0002-4763-5009
Article History
Received: 26 July 2025
Revised: 27 January 2026
Accepted: 24 February 2026
First Online: 12 May 2026
Competing interests
: The authors declare the following patent applications related to the findings of this study, all filed by KIST: • patent no. 10-2932728 (Republic of Korea) and application no. 18/598,746 (USA), covering the use of MECP2 as a biomarker for depression diagnosis and as a therapeutic target. • application nos. 10-2025-0003282 (Republic of Korea) and 19/322,108 (USA), covering the development of a Cre-dependent viral system for gene regulation of MeCP2; a corresponding PCT/KR2025/012274 application has also been filed.