Swain, Ansuman https://orcid.org/0000-0002-8067-7921
Pearson, Natalie
Willis, Scott A. https://orcid.org/0000-0001-8624-1427
Johnson, William https://orcid.org/0000-0002-0347-4354
Article History
Received: 14 April 2025
Revised: 18 November 2025
Accepted: 18 December 2025
First Online: 7 January 2026
Competing interests
: The authors declare no competing interests.
: All methods were carried out in accordance with the Declaration of Helsinki (2013) and the UK Biobank ethical and governance frameworks. The UK Biobank obtained research ethical approval from the Northwest Multi-centre Research Ethics Committee (REC reference: 11/NW/0382). The present study was conducted under the UK Biobank application number 80843. Informed consent was obtained by the UK Biobank from all participants at recruitment, including consent for follow-up and linkage to health-related records.