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Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation

Crossref DOI link: https://doi.org/10.1038/s41368-026-00432-9

Published Online: 2026-04-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Tao, Ran https://orcid.org/0000-0002-9296-3992
Liu, Sufang

Crawford, Joshua

Kramer, Phillip

Bender, Steven

Tao, Feng https://orcid.org/0000-0002-0623-6298
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute of Dental and Craniofacial Research (R01DE031255)

U.S. Department of Health & Human Services | NIH | National Institute of Dental and Craniofacial Research (R01DE032061)

U.S. Department of Health & Human Services | NIH | National Institute of Dental and Craniofacial Research (R03DE031822)
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Text and Data Mining valid from 2026-04-17

Version of Record valid from 2026-04-17
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Article History

Received: 20 June 2025

Revised: 26 January 2026

Accepted: 29 January 2026

First Online: 17 April 2026

Competing interests

: The authors declare no competing interests.

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