Sun, Xuezheng https://orcid.org/0009-0003-9145-3194
Mowla, Sanjida
Simpson, Annie N.
Lahiri, Aditi
Edelman, Dana
Liu, Yusu
Corman, Shelby
Fuentes, Daniel
Dukhovny, Dmitry https://orcid.org/0000-0003-3327-2996
Kuzniewicz, Michael W. https://orcid.org/0000-0002-3271-2999
Funding for this research was provided by:
Chiesi Pharmaceuticals | Chiesi Foundation
Article History
Received: 29 May 2025
Revised: 11 December 2025
Accepted: 9 February 2026
First Online: 24 February 2026
Competing interests
: The authors affiliated with Chiesi are employee of the funding organization. The authors declare no other conflicts of interest.
: This study was conducted in accordance with the relevant guidelines and regulations. The study protocol was reviewed by the Kaiser Permanente Northern California Institutional Review Board (IRB), which granted an exemption and approved a waiver of informed consent and authorization as the study involved analysis of existing data and records without direct patient identifiers (IRB # 00001045). Therefore, informed consent from individual participants was not required. No identifiable images of human participants are included in the manuscript.