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Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O6-methylguanine DNA methyltransferase (MGMT) expression and reactive oxygen species (ROS)-mediated DNA damage in glioblastoma

Crossref DOI link: https://doi.org/10.1038/s41374-021-00666-7

Published Print: 2022-02

Update policy: https://doi.org/10.1016/elsevier_cm_policy

Authors

Jin, Lei http://orcid.org/0000-0003-0432-4929
Kiang, Karrie Mei-Yee

Cheng, Stephen Yin

Leung, Gilberto Ka-Kit http://orcid.org/0000-0003-3147-3057
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Article Title: Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O6-methylguanine DNA methyltransferase (MGMT) expression and reactive oxygen species (ROS)-mediated DNA damage in glioblastoma

Journal Title: Laboratory Investigation

CrossRef DOI link to publisher maintained version: https://doi.org/10.1038/s41374-021-00666-7

Content Type: article

Copyright: © 2021 United States & Canadian Academy of Pathology.

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