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BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

Crossref DOI link: https://doi.org/10.1038/s41375-021-01123-6

Published Online: 2021-02-01

Published Print: 2021-05

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Estupiñán, H. Yesid https://orcid.org/0000-0002-9388-5957
Wang, Qing

Berglöf, Anna

Schaafsma, Gerard C. P. https://orcid.org/0000-0001-6351-7486
Shi, Yuye

Zhou, Litao

Mohammad, Dara K. https://orcid.org/0000-0001-9201-0991
Yu, Liang

Vihinen, Mauno

Zain, Rula https://orcid.org/0000-0001-8327-846X
Smith, C. I. Edvard https://orcid.org/0000-0003-1907-3392
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Text and Data Mining valid from 2021-02-01

Version of Record valid from 2021-02-01
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Article History

Received: 26 June 2020

Revised: 11 December 2020

Accepted: 7 January 2021

First Online: 1 February 2021

Compliance with ethical standards

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: The authors declare that they have no conflict of interest.

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