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Genome-wide CRISPR/Cas9 library screening identified OGDH as a regulator of disease progress and resistance to decitabine in myelodysplastic neoplasm by reprogramming glutamine metabolism

Crossref DOI link: https://doi.org/10.1038/s41375-024-02377-6

Published Online: 2024-09-03

Published Print: 2024-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Xu, Xiaoyan

Qi, Jiaqian

Wang, Hong

Zhang, Ziyan

Pan, Tingting

Li, Xueqian

Yang, Jingyi

Han, Haohao

Guo, Mengting

Zhou, Meng

Cai, Chengsen

Tang, Yaqiong

Hou, Qixiu https://orcid.org/0009-0000-8296-8063
Chen, Suning

Wu, Depei

Han, Yue https://orcid.org/0000-0002-7560-7195
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Version of Record valid from 2024-09-03
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Article History

Received: 21 April 2024

Revised: 6 August 2024

Accepted: 8 August 2024

First Online: 3 September 2024

Competing interests

: The authors declare no competing interests.

: Informed consent was obtained from all patients before data collection. The study was approved by the Research Ethics Review Committee of the First Affiliated Hospital of Soochow University.

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