Rheingold, Susan R. https://orcid.org/0000-0001-8025-6767
Bhojwani, Deepa https://orcid.org/0000-0002-7559-7927
Ji, Lingyun
Xu, Xinxin https://orcid.org/0009-0000-3989-4169
Devidas, Meenakshi https://orcid.org/0000-0002-1099-3478
Kairalla, John A.
Shago, Mary
Heerema, Nyla A.
Carroll, Andrew J.
Breidenbach, Heather
Borowitz, Michael
Wood, Brent L. https://orcid.org/0000-0001-7414-3969
Angiolillo, Anne L.
Asselin, Barbara L.
Bowman, W. Paul
Brown, Patrick https://orcid.org/0000-0002-8653-1069
Dreyer, ZoAnn E.
Dunsmore, Kimberly P.
Hilden, Joanne M.
Larsen, Eric
Maloney, Kelly
Matloub, Yousif
Mattano, Leonard A. https://orcid.org/0000-0002-8409-0589
Winter, Stuart S. https://orcid.org/0000-0003-3583-7727
Gore, Lia
Winick, Naomi J. https://orcid.org/0000-0002-6636-3870
Carroll, William L. https://orcid.org/0000-0003-1550-4167
Hunger, Stephen P.
Raetz, Elizabeth A. https://orcid.org/0000-0002-8547-1658
Loh, Mignon L. https://orcid.org/0000-0003-4099-4700
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Cancer Institute (U10CA13539, U10CA29139, U10CA98543, U10CA98413, U10CA180886, U10CA180899, U24CA114766, U24CA196173, U10CA13539, U10CA13539, U10CA13539, U10CA13539, U10CA13539, U10CA13539, U10CA13539)
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
St. Baldrick's Foundation
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute
Article History
Received: 7 May 2024
Revised: 11 August 2024
Accepted: 21 August 2024
First Online: 11 September 2024
Competing interests
: The authors declare no competing interests.
: The trial protocols were approved by the National Cancer Institute and by the Pediatric Central Institutional Review Board and by each trial center Institutional Review Board. All patients or a parent/guardian provided written informed consent for clinical trial enrollment. The independent Children’s Oncology Group, and historic Children’s Cancer Group and Pediatric Oncology Group, data and safety monitoring committees met regularly to review trial safety and efficacy data according to its charter and standard operating procedures. All individual trial references which include NCI registration numbers are found in Table .