Okamoto, Haruya
Mizutani, Shinsuke https://orcid.org/0000-0002-6498-1755
Tsukamoto, Taku
Katsuragawa-Taminishi, Yoko
Kawaji-Kanayama, Yuka https://orcid.org/0000-0003-1821-3023
Mizuhara, Kentaro
Muramatsu, Ayako
Isa, Reiko
Fujino, Takahiro https://orcid.org/0000-0001-7817-093X
Shimura, Yuji
Ichikawa, Koji https://orcid.org/0000-0002-4625-3711
Kuroda, Junya https://orcid.org/0000-0001-6130-1550
Article History
Received: 24 August 2024
Revised: 8 October 2024
Accepted: 10 October 2024
First Online: 22 October 2024
Competing interests
: This work is partly supported by Taiho Pharmaceutical Co., Ltd. J.K. is a consultant for Janssen Pharmaceutical, Abbvie, Pfizer, BeiGene, and Bristol-Myers Squibb (BMS), has received research funding from Kyowa Kirin, Chugai Pharmaceutical, Japan Blood Product Organization, Sumitomo Pharmaceutical, Otsuka Pharmaceutical, Asahikasei, and Mochida Pharmaceutical and has received honoraria from Janssen Pharmaceutical, Kyowa Kirin, Chugai Pharmaceutical, Ono Pharmaceutical, Sanofi, BMS, Novartis, Abbvie, Pfizer, and Astellas Pharmaceutical. S.M. has received honoraria from Sanofi and Ono Pharmaceutical. T.T. has received honoraria from BMS, Janssen Pharmaceutical, Sanofi, Kyowa Kirin, and Chugai Pharmaceutical. T.F. has received honoraria from Takeda Pharmaceutical. Y.S. has received honoraria from Ono Pharmaceutical, BMS, Janssen Pharmaceutical, Sanofi, Kyowa Kirin, Takeda Pharmaceutical, and Chugai Pharmaceutical. K.I. is an employee of Taiho Pharmaceutical.
: All methods were performed in accordance with the relevant guidelines and regulations. This study was conducted in accordance with the principles of the Declaration of Helsinki and was approved by the institutional review board of Kyoto Prefectural University of Medicine (RBMR-G-124-15). Written informed consent was obtained from all patients for the use of their BM cells. All animal care and treatments were approved by the Institutional Animal Care and Use Committee of Taiho Pharmaceutical Co., Ltd., and all procedures for animal experiments were performed according to the company’s guidelines.