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Authors
Gharaee, Nadia
Wegrzyn-Woltosz, Joanna
Jiang, Jihong
Akhade, Vijay Suresh https://orcid.org/0000-0001-7645-6627
Bridgers, Joshua
Stubbins, Ryan J. https://orcid.org/0000-0002-4718-5212
Hiwase, Devendra https://orcid.org/0000-0002-6666-3056
Kutyna, Monika M. https://orcid.org/0000-0003-2315-091X
Chan, Onyee https://orcid.org/0000-0003-2872-1961
Komrokji, Rami
Padron, Eric https://orcid.org/0000-0002-4707-7916
Deng, Yu
Cole, Gary
Umlandt, Patricia
Fuller, Megan
Kim, Ada
Karsan, Aly https://orcid.org/0000-0001-6753-892X
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Funding
Funding for this research was provided by:
Terry Fox Research Institute Program Project Grant
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Article History
Received: 28 April 2024
Revised: 21 December 2024
Accepted: 11 February 2025
First Online: 25 February 2025
Competing interests
: The authors declare no competing interests.
: All methods were conducted in accordance with relevant guidelines and regulations. Human umbilical cord blood cells were obtained with informed consent under a protocol approved by the University of British Columbia (UBC) Research Ethics Board (REB). Primary umbilical cord blood cells and MDS samples were collected with patient or guardian consent from the Hematology Cell Bank of British Columbia under protocols approved by the UBC REB and institutional review boards at the Royal Adelaide Hospital and Moffitt Cancer Center. Mice were bred and maintained at the BC Cancer Research Center Animal Resources Facility (Vancouver, BC, Canada), with experimental protocols approved by the UBC Animal Care Committee. Ethics approval for xenotransplantation assays (A22-0169) and human cell use (H19-01373, H19-01430) was obtained from the UBC REB for the experiments in this study.
