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Authors
Nomiyama, Tomoko https://orcid.org/0009-0005-6427-4259
Setoyama, Daiki https://orcid.org/0000-0002-4514-7546
Yamanaka, Ikumi
Shimo, Masatoshi
Miyawaki, Kohta
Yamauchi, Takuji
Jinnouchi, Fumiaki
Sakoda, Teppei
Sasaki, Kensuke https://orcid.org/0000-0003-1302-3511
Shima, Takahiro
Kikushige, Yoshikane https://orcid.org/0000-0002-7721-1696
Mori, Yasuo
Akashi, Koichi https://orcid.org/0000-0001-7763-5723
Kato, Koji
Kunisaki, Yuya https://orcid.org/0000-0003-0141-7038
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Funding
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (21H02950)
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Article History
Received: 1 September 2024
Revised: 15 January 2025
Accepted: 12 February 2025
First Online: 11 March 2025
Competing interests
: The authors declare no competing financial interests related to this study. Koji Kato; Honoraria: AbbVie, Bristol-Myers Squibb, Chugai, Dainippon-Sumitomo, Janssen, Kyowa Kirin, MSD, AbbVie, Ono, Gilead Sciences, Novartis; Consulting or Advisory Role: AbbVie, AstraZeneca, Chugai, Daiichi Sankyo, Eisai, Janssen, Bristol-Myers Squibb, Novartis, Gilead Sciences; Research Funding: AbbVie, Astellas, MSD, Bristol-Myers Squibb, Chugai, Daiichi Sankyo, Eisai, Janssen, Kyowa Kirin, Novartis, Ono, Gilead Sciences. All conflicts of interest declared are unrelated to the content of this manuscript.
: This study was a retrospective analysis conducted in accordance with the principles outlined in the Declaration of Helsinki and was approved by the Ethics Committee of Kyushu University (IRB numbers: 22213 and 23399). Informed consent was obtained using an opt-out methodology, whereby study details were disclosed on the institutional website, allowing participants the opportunity to decline participation. Data and CSF samples from individuals who did not opt out were included in the analysis. All collected data were anonymized prior to analysis to safeguard the privacy of participants.
