Mecklenbrauck, Rabea
Borchert, Nora
Gabdoulline, Razif
Poll, Piroska
Funke, Carolin
Brandes, Maximilian
Dallmann, Louisa-Kristin
Fiedler, Walter
Krauter, Jürgen
Trummer, Arne
Hertenstein, Bernd
Müller, Martin
Lübbert, Michael https://orcid.org/0000-0003-1186-1650
Schwalenberg, Monika
Voss, Andreas https://orcid.org/0000-0001-9647-5024
Di Donato, Nataliya
Bergmann, Anke https://orcid.org/0000-0002-1367-2725
Gaidzik, Verena https://orcid.org/0000-0001-6530-3406
Döhner, Konstanze https://orcid.org/0000-0002-2261-9862
Döhner, Hartmut https://orcid.org/0000-0003-2116-5536
Ganser, Arnold
Heidel, Florian H. https://orcid.org/0000-0003-2438-1955
Thol, Felicitas R. https://orcid.org/0000-0001-5848-6152
Heuser, Michael https://orcid.org/0000-0001-5318-9044
Funding for this research was provided by:
Deutsche Krebshilfe (70115737)
Deutsche Forschungsgemeinschaft (HE6233/15-1 and HE6233/16-1)
Article History
Received: 23 December 2024
Revised: 8 April 2025
Accepted: 11 April 2025
First Online: 28 April 2025
Competing interests
: AV declares honoraria from BMS/Celgene, Delbert, Novartis, Pfizer, SOBI and travel support from Amgen. AT declares paid consultancy from BMS and Janssen. WF declares personal fees and non-financial support from AbbVie; grants, personal fees, and non-financial support from Amgen and Pfizer; and personal fees from Jazz Pharmaceuticals, Celgene, MorphoSys, Ariad/Incyte, Stemline Therapeutics, Clinigen, Daiichi Sankyo, Otsuka and Servier outside the submitted work; in addition, research support from Apis; patent issued with Amgen and support for medical writing for Amgen, Pfizer, and AbbVie. KD declares consultancy with honoraria from AbbVie, Janssen, Jazz, Novartis, Bristol Myers Squibb, Celgene; clinical research funding to institution from Novartis, AbbVie, Astellas, Bristol Myers Squibb, Celgene, Jazz Pharmaceuticals, Kronos Bio, Servier. HD declares honoraria from AbbVie, AstraZeneca, Gilead, Janssen, Jazz, Pfizer, Servier, Stemline, Syndax; clinical research funding to institution from AbbVie, Astellas, Bristol Myers Squibb, Celgene, Jazz Pharmaceuticals, Kronos Bio, Servier; Travel, accommodations, expenses from Abbvie, Servier. FHH served as an advisor for Novartis, CTI, Celgene/BMS, Janssen, Abbvie, GSK, Merck and AOP and received research funding from Novartis, Celgene/BMS and CTI. MH declares honoraria from Abbvie, Eurocept, Jazz Pharmaceuticals, Janssen, Novartis, Takeda, paid consultancy for Abbvie, Agios, BMS, Daiichi Sankyo, Glycostem, Jazz Pharmaceuticals, Kura Oncology, Novartis, Pfizer, PinotBio, Roche, Tolremo, and research funding to his institution from Abbvie, Agios, Astellas, Bayer Pharma AG, BergenBio, Daiichi Sankyo, Glycostem, Jazz Pharmaceuticals, Loxo Oncology, Novartis, Pfizer, PinotBio, Roche.
: Written informed consent was obtained according to the Declaration of Helsinki and the study was approved by the local ethics review committee of Hannover Medical School (ethical vote 936-2011 and 1187-2011). Since 2012 all patients were included in the AMLSG-BiO registry. All described methods were performed in accordance with the relevant guidelines and regulations.