Khouja, Mouhamad https://orcid.org/0000-0002-9892-9461
Kehden, Britta
Blair, Derek
Kuffer, Christian
Wagner, Steve
Versteegen, Tim
Nakov, Philipp
Brüggemann, Monika
Baldus, Claudia https://orcid.org/0000-0002-0748-834X
Belada, David
Nowakowski, Grzegorz S. https://orcid.org/0000-0002-6955-9393
Schilhabel, Anke
Darzentas, Nikos
Pott, Christiane https://orcid.org/0009-0005-9260-8340
,
Article History
Received: 28 March 2025
Revised: 23 July 2025
Accepted: 1 September 2025
First Online: 27 October 2025
Competing interests
: MK, BK, TV, PN, AS, and ND: nothing to declare. DB, CK and SW: Employees of MorphoSys, MB: Advisory Board: Incyte, Amgen, Speaker: BD, Janssen, Pfizer, Amgen, research funding: Amgen., CB: Consultancy: Astellas, BMS, AstraZeneca, Amgen, Jazz Pharmaceuticals, Gilead, and Janssen., GN: Consultancy: AbbVie, ADC Therapeutics, Bantam Pharmaceutical LLC, Blueprint Medicines, Bristol-Myers Squibb, Celgene Corporation, Curis, Debiopharm, F Hoffmann-La Roche Limited, Fate Therapeutics, Genentech, Genmab, Incyte, Karyopharm Therapeutics, Kite Pharma, Kymera Therapeutics, MEI Pharma, MorphoSys AG, Regeneron, Roche, Ryvu Therapeutics, Seagen, Selvita Inc, TG Therapeutics, Urogen., DB: Consultancy, Research support: Roche, Seattle Genetics, Takeda, Morphosys, Abbvie, Gilead Sciences, BMS, Beigene, Astra Zeneca, Sobi, Regeneron., CP: research Funding: Roche, MorphoSys, Honoraria: Lilly, Novartis, Kite, Gilead, Roche.
: The trial was led according to the Declaration of Helsinki. All patients gave their written informed consent after have been informed about the purpose and investigational nature of the trial. Prior to initiation, the clinical trial including molecular analysis received approval by the respective ethics committee of each participating country: University of Vienna, Austria, Erasmus Hospital, Belgium, University Hospital Hradec Kralove, Czech Republic, University of Rouen, France, University of Göttingen, Germany, Research Ethics committee of Sabadell, Spain, Western Institutional Review Board, Mayo Clinic, Advarra institutional Review Board and US Oncology Inc. Institutional Review Board, USA.