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Authors
Iaccarino, Ingram https://orcid.org/0000-0001-7324-993X
Hartmann, Alina M. https://orcid.org/0009-0002-0638-0000
Yalcin, Fatih https://orcid.org/0000-0001-6325-9018
Mondal, Mayukh https://orcid.org/0000-0003-0122-0323
Bozzetti, Cecilia
Wolgast, Nadine https://orcid.org/0000-0002-3068-3899
Loeffen, Jan L. C. https://orcid.org/0000-0002-2537-5779
Boer, Judith M. https://orcid.org/0000-0003-4848-7789
Brüggemann, Monika
Baldus, Claudia D. https://orcid.org/0000-0002-0748-834X
Cario, Gunnar
Klapper, Wolfram https://orcid.org/0000-0001-7208-4117
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Funding
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Deutsche Forschungsgemeinschaft (CATCH ALL (KFO 5010))
Stichting Kinderen Kankervrij (grant number 393)
Stichting Kinderen Kankervrij (grant number 393)
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Article History
Received: 22 October 2025
Revised: 23 February 2026
Accepted: 17 March 2026
First Online: 23 March 2026
Competing interests
: II, AMH, MM, NW, CB, FY, JLCL and JMB have no competing financial interests in relation to the work described; GC received travel support from Jazz Pharma. WK reports research funding from Roche, Amgen, Regeneron, Takeda, Janssen and Incyte with all activities on behalf of the institution and without any relevance to the current project. CDB reports advisory and speaker honoraria from AstraZeneca, Bristol Myers Squibb, Janssen, Kite, Novartis, Jazz Pharmaceutical, Astellas, and Amgen also without any relevance to the current project.
: All methods were performed in accordance with the relevant guidelines and regulations. Approval has been obtained from the ethics advisory committee of the Medical Faculty of the University of Kiel (D464/17). Informed consent was obtained from all participants.
