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Authors
Ghete, Tabita https://orcid.org/0009-0005-8602-3020
Gaschler, Laura
Krumbholz, Manuela https://orcid.org/0000-0002-4416-0394
Sembill, Stephanie
Behrens, Yvonne Lisa
Karow, Axel
Wölfl, Matthias
Auer, Franziska https://orcid.org/0000-0002-1193-6002
Hauer, Julia https://orcid.org/0000-0002-4058-3058
Carta, Maria Giulia https://orcid.org/0009-0006-4541-2270
Ferrazzi, Fulvia https://orcid.org/0000-0003-4011-4638
Hutter, Stephan https://orcid.org/0000-0003-2432-8898
Horn, Anselm H. C.
Sticht, Heinrich https://orcid.org/0000-0001-5644-045X
Schlegel, Paul-Gerhardt
Metzler, Markus https://orcid.org/0000-0002-4523-1676
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Funding
Funding for this research was provided by:
German Federal Ministry of Education and Research
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Article History
Received: 17 December 2025
Revised: 5 March 2026
Accepted: 27 March 2026
First Online: 24 April 2026
Competing interests
: The authors declare no competing interests.
: The CML-PAED-II trial was conducted in accordance with the Declaration of Helsinki and approved by the institutional ethics boards of the medical faculties of the Technical University, Dresden, Germany and the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany (EK282 122 006 and EK 236_18 B). For genetic analyses, all participants or legal guardians provided informed consent in accordance with the Declaration of Helsinki.
