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Article History

Received: 18 May 2020

Revised: 11 September 2020

Accepted: 27 October 2020

First Online: 11 November 2020

Compliance with ethical standards

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: The authors have declared that there are no conflicts of interest relating to the subject of this study. Interests from the past three years are as follows. Dr. Kishi received speaker’s honoraria from Daiichi Sankyo, Dainippon Sumitomo, Eisai, Janssen, Otsuka, Meiji, Mochida, MSD, and Tanabe-Mitsubishi (Yoshitomi); as well as research grants from the Japanese Ministry of Health, Labor and Welfare　(H29-Seishin-Ippan-001, 19GC1012), Grant-in-Aid for Scientific Research (C), and Fujita Health University School of Medicine. Dr. Ikuta has no conflicts of interest with any company. Dr. Matsuda has received speaker’s honoraria from Dainippon Sumitomo, Janssen, Kyowa, Otsuka, Tanabe-Mitsubishi, and Yoshitomi. Dr. Sakuma has received speaker’s honoraria from Eisai, Kissei, Meiji, Otsuka, and Torii; and has received a Fujita Health University School of Medicine research grant, as well as a Grant-in-Aid for Young Scientists (B). Dr. Okuya has received speaker’s honoraria from Meiji. Dr. Mishima received research support from the Japanese Ministry of Health, Labor and Welfare (H29-Seishin-Ippan-001, 19GC1012) and the Japanese Ministry of Education, Culture, Sports, Science and Technology Collaborative research fund with Taisho; as well as speaker’s honoraria from Eisai, MSD, Takeda, Astellas, Pfizer, Otsuka, Mochida, Mitsubishi Tanabe, Yoshitomi, and Janssen; and research grants from Eisai, Nobelpharma, Otsuka, and Takeda. Dr. Iwata received speaker’s honoraria from Dainippon Sumitomo, Eli Lilly, GlaxoSmithKline, Janssen, Yoshitomi, Otsuka, Takeda, Meiji, and Pfizer; along with research grants from Daiichi Sankyo, Takeda, Dainippon Sumitomo Eisai, Meiji Tanabe-Mitsubishi and Otsuka.