Wang, Xin http://orcid.org/0000-0003-1524-2902
Xie, Hong
Chen, Tian
Cotton, Andrew S.
Salminen, Lauren E.
Logue, Mark W.
Clarke-Rubright, Emily K. http://orcid.org/0000-0003-3553-2990
Wall, John
Dennis, Emily L.
O’Leary, Brian M.
Abdallah, Chadi G. http://orcid.org/0000-0001-5783-6181
Andrew, Elpiniki
Baugh, Lee A.
Bomyea, Jessica
Bruce, Steven E.
Bryant, Richard http://orcid.org/0000-0002-9607-819X
Choi, Kyle
Daniels, Judith K.
Davenport, Nicholas D.
Davidson, Richard J. http://orcid.org/0000-0002-8506-4964
DeBellis, Michael
deRoon-Cassini, Terri
Disner, Seth G. http://orcid.org/0000-0003-3635-9421
Fani, Negar http://orcid.org/0000-0002-7720-252X
Fercho, Kelene A.
Fitzgerald, Jacklynn
Forster, Gina L.
Frijling, Jessie L.
Geuze, Elbert http://orcid.org/0000-0003-3479-2379
Gomaa, Hassaan
Gordon, Evan M.
Grupe, Dan http://orcid.org/0000-0003-4927-7572
Harpaz-Rotem, Ilan http://orcid.org/0000-0002-6066-9406
Haswell, Courtney C.
Herzog, Julia I. http://orcid.org/0000-0001-8326-5466
Hofmann, David
Hollifield, Michael
Hosseini, Bobak
Hudson, Anna R.
Ipser, Jonathan
Jahanshad, Neda http://orcid.org/0000-0003-4401-8950
Jovanovic, Tanja
Kaufman, Milissa L.
King, Anthony P. http://orcid.org/0000-0002-0764-9625
Koch, Saskia B. J. http://orcid.org/0000-0002-3628-6712
Koerte, Inga K. http://orcid.org/0000-0003-1281-9286
Korgaonkar, Mayuresh S. http://orcid.org/0000-0002-1339-2221
Krystal, John H. http://orcid.org/0000-0001-6952-1726
Larson, Christine
Lebois, Lauren A. M. http://orcid.org/0000-0001-5816-9181
Levy, Ifat http://orcid.org/0000-0001-7851-9070
Li, Gen
Magnotta, Vincent A.
Manthey, Antje
May, Geoffrey
McLaughlin, Katie A.
Mueller, Sven C. http://orcid.org/0000-0003-1661-3840
Nawijn, Laura
Nelson, Steven M.
Neria, Yuval
Nitschke, Jack B.
Olff, Miranda
Olson, Elizabeth A.
Peverill, Matthew
Phan, K. Luan
Rashid, Faisal M.
Ressler, Kerry http://orcid.org/0000-0002-5158-1103
Rosso, Isabelle M.
Sambrook, Kelly
Schmahl, Christian
Shenton, Martha E.
Sierk, Anika
Simons, Jeffrey S.
Simons, Raluca M.
Sponheim, Scott R. http://orcid.org/0000-0002-2782-0856
Stein, Murray B. http://orcid.org/0000-0001-9564-2871
Stein, Dan J. http://orcid.org/0000-0001-7218-7810
Stevens, Jennifer S. http://orcid.org/0000-0003-4674-0314
Straube, Thomas
Suarez-Jimenez, Benjamin http://orcid.org/0000-0002-4765-2458
Tamburrino, Marijo http://orcid.org/0000-0002-9034-8347
Thomopoulos, Sophia I.
van der Wee, Nic J. A.
van der Werff, Steven J. A.
van Erp, Theo G. M. http://orcid.org/0000-0002-2465-2797
van Rooij, Sanne J. H. http://orcid.org/0000-0002-0160-7248
van Zuiden, Mirjam
Varkevisser, Tim
Veltman, Dick J.
Vermeiren, Robert R. J. M.
Walter, Henrik http://orcid.org/0000-0002-9403-6121
Wang, Li http://orcid.org/0000-0002-1459-3412
Zhu, Ye
Zhu, Xi
Thompson, Paul M.
Morey, Rajendra A.
Liberzon, Israel http://orcid.org/0000-0002-4990-556X
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH110483, R21MH098198, L30 MH114379, R01 MH111671, K23 MH090366-01, R01MH043454, T32MH018931, K24MH71434, R01MH63407, R01MH61744, MH101380, R01MH105535, 1R21MH102634, R01MH111671, R01MH111671, R01MH117601, MH098212, MH071537, F32MH109274, 1R21MH102634, R01MH103291, R01MH105355, MH098212, MH071537, K01MH118428, R01MH105355-01A)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Veterans Affairs | VISN6 MIRECC
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (K99NS096116)
U.S. Department of Defense (W81XWH-10-1-0925, W81XWH-10-1-0925, W81XWH-10-1-0925, W81XWH-08-2-0159, W81XWH08-2-0159, W81XWH-10-1-0925, W81XWH-10-1-0925, W81XWH08-2-0159, W81XWH-12-2-0012)
Brain and Behavior Research Foundation
South Dakota Governor’s Research Center Grant
U.S. Department of Veterans Affairs (CX001600 VA CDA, VA RR&D 1IK2RX000709, VA CSR&D 1IK2CX001680)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Department of Health | National Health and Medical Research Council (1073041)
Deutsche Forschungsgemeinschaft (DA 1222/4-1, WA 1539/8-2, DA 1222/4-1, WA 1539/8-2, DA 1222/4-1, WA 1539/8-2, SFB/ TRR 58: C06, C07, DA 1222/4-1, WA 1539/8-2)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (P30HD003352, HD071982, HD085850, P30HD003352, HD071982, HD085850)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (5U01AA021681-08, R01AA12479)
U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (K24DA028773)
U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Brain and Behavior Research Foundation
Brain and Behavior Research Foundation
Academisch Medisch Centrum (110614, 110614, 110614, 110614, 110614)
ZonMw (40-00812-98-10041, 40-00812-98-10041, 40-00812-98-10041, 40-00812-98-10041, 40-00812-98-10041)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01AG05987)
Michael J. Fox Foundation for Parkinson’s Research (MJFF14848)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (UL1TR000454, UL1TR000454)
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development
U.S. Department of Health & Human Services | NIH | National Center for Research Resources (M01RR00039, M01RR00039)
U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism
U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Bijzonder Onderzoeksfonds (01J05415)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Dana Foundation
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development
U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences
U.S. Department of Health & Human Services | NIH | National Center for Research Resources
Brain and Behavior Research Foundation
Brain and Behavior Research Foundation
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Brain and Behavior Research Foundation
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
U.S. Department of Health & Human Services | National Institutes of Health (U54 EB020403, R56AG058854, R01MH116147, R01MH111671, P41 EB015922)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
Article History
Received: 9 January 2020
Revised: 29 October 2020
Accepted: 18 November 2020
First Online: 7 December 2020
Change Date: 21 November 2022
Change Type: Update
Change Details: For Author K. Luan Phan, given name and family name tagging is updated.
Compliance with ethical standards
:
: Dr CGA has served as a consultant, speaker and/or on advisory boards for FSV7, Lundbeck, Psilocybin Labs, Genentech and Janssen, and editor of Chronic Stress for Sage Publications, Inc.; he has filed a patent for using mTOR inhibitors to augment the effects of antidepressants (filed on August 20, 2018). Dr RJD is the founder and president of, and serves on the board of directors for, the non-profit organization Healthy Minds Innovations, Inc. Dr NJ received partial research support from Biogen, Inc. (Boston, USA) for research unrelated to the content of this paper. Dr JHK is a consultant for AbbVie, Inc., Amgen, Astellas Pharma Global Development, Inc., AstraZeneca Pharmaceuticals, Biomedisyn Corporation, Bristol-Myers Squibb, Eli Lilly and Company, Euthymics Bioscience, Inc., Neurovance, Inc., FORUM Pharmaceuticals, Janssen Research & Development, Lundbeck Research USA, Novartis Pharma AG, Otsuka America Pharmaceutical, Inc., Sage Therapeutics, Inc., Sunovion Pharmaceuticals, Inc., and Takeda Industries; is on the Scientific Advisory Board for Lohocla Research Corporation, Mnemosyne Pharmaceuticals, Inc., Naurex, Inc., and Pfizer; is a stockholder in Biohaven Pharmaceuticals; holds stock options in Mnemosyne Pharmaceuticals, Inc.; holds patents for Dopamine and Noradrenergic Reuptake Inhibitors in Treatment of Schizophrenia, US Patent No. 5,447,948 (issued September 5, 1995), and Glutamate Modulating Agents in the Treatment of Mental Disorders, U.S. Patent No. 8,778,979 (issued July 15, 2014); filed a patent for Intranasal Administration of Ketamine to Treat Depression. U.S. Application No. 14/197,767 (filed on March 5, 2014); filed US application or Patent Cooperation Treaty international application No. 14/306,382 (filed on June 17, 2014); and filed a patent for using mTOR inhibitors to augment the effects of antidepressants (filed on August 20, 2018). Dr PMT received partial research support from Biogen, Inc. (Boston, USA) for research unrelated to the topic of this paper. No other authors reported conflicts of interest.