Teichman, Emily M.
Hu, Jianping
Lin, Hsiao-yun
Fisher-Foye, Rachel L.
Blando, Anthony
Hu, Xiaoping
Kaniskan, H. Ümit https://orcid.org/0000-0001-5327-832X
Montgomery, Sarah E.
Cai, Min
Parise, Lyonna F. https://orcid.org/0000-0002-7527-8977
Wang, Jun https://orcid.org/0000-0002-4291-2134
Russo, Scott J. https://orcid.org/0000-0002-6470-1805
Han, Ming-Hu
Jin, Jian https://orcid.org/0000-0002-2387-3862
Morel, Carole https://orcid.org/0000-0002-5076-1938
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120637, R01MH120514, F31MH131358, R01MH133299, R01MH104559, R01MH127820)
U.S. Department of Veterans Affairs (I01BX005722)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (1S10OD025132, 1S10OD028504)
Article History
Received: 1 March 2024
Revised: 16 December 2024
Accepted: 20 March 2025
First Online: 8 April 2025
Competing interests
: The authors declare no competing interests.
: JJ is a cofounder and equity shareholder in Cullgen, Inc., a scientific cofounder and scientific advisory board member of Onsero Therapeutics, Inc., and a consultant for Cullgen, Inc., EpiCypher, Inc., Accent Therapeutics, Inc, and Tavotek Biotherapeutics, Inc. The Jin laboratory received research funds from Celgene Corporation, Levo Therapeutics, Inc., Cullgen, Inc. and Cullinan Oncology, Inc.
: The study is reported in accordance with the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines (). All experiments were conducted on mice; thereby, informed consent was not required for human participants. All efforts were made to minimize the number of animals used in the experiments and to limit their distress and suffering. All methods and experiments were performed in accordance with the guidelines of the Institutional Animal Care and Use Committee at Mount Sinai (IACUC - MSSM). Experimental protocols were approved (IACUC at Mount Sinai, protocol #LA10-00067) by the Institutional Animal Care and Use Committee at MountSinai.