Wildermuth, Erin
Patton, Michael S.
Cortes-Gutierrez, Marcia
Jinwala, Zeal https://orcid.org/0009-0005-5062-0827
Grissom, Benjamin H.
Campbell, Rianne R.
Kranzler, Henry R. https://orcid.org/0000-0002-1018-0450
Lobo, Mary Kay https://orcid.org/0000-0002-9419-2079
Ament, Seth A. https://orcid.org/0000-0001-6443-7509
Mathur, Brian N. https://orcid.org/0000-0003-2912-8625
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (R01 AA024845, R01 AA024845, R01 AA024845, R01 AA024845, R01 AA024845)
U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (U01 DA051947, U01 DA051947)
U.S. Department of Veterans Affairs (#I01 BX004820)
Article History
Received: 9 February 2024
Revised: 22 March 2025
Accepted: 2 April 2025
First Online: 16 April 2025
Competing interests
: Dr. Kranzler is a member of advisory boards for Altimmune, Clearmind Medicine, Dicerna Pharmaceuticals, Enthion Pharmaceuticals, and Sophrosyne Pharmaceuticals; a consultant to Sobrera Pharmaceuticals and Altimmune; the recipient of research funding and medication supplies for an investigator-initiated study from Alkermes; a member of the American Society of Clinical Psychopharmacology’s Alcohol Clinical Trials Initiative, which was supported in the last three years by Alkermes, Dicerna, Ethypharm, Lundbeck, Mitsubishi, Otsuka, and Pear Therapeutics; and a holder of U.S. patent 10,900,082 titled: “Genotype-guided dosing of opioid agonists,” issued 26 January 2021. All other authors declare they have nothing to disclose.
: Animal studies were performed in accordance with NIH guidelines and were approved by the Institutional Animal Care and Use Committee of the University of Maryland Baltimore (Protocol # 0522009). The central Veterans Affairs (VA) institutional review board (IRB) approved the Million Veteran Program study. All relevant ethical regulations for work with human subjects were followed in the conduct of the study and informed consent was obtained from all participants.