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Alzheimer’s disease patient brain extracts induce multiple pathologies in novel vascularized neuroimmune organoids for disease modeling and drug discovery

Crossref DOI link: https://doi.org/10.1038/s41380-025-03041-w

Published Online: 2025-05-02

Published Print: 2025-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ji, Yanru

Chen, Xiaoling https://orcid.org/0000-0002-2271-1140
Wang, Zhen

Meek, Connor Joseph

McLean, Jenna Lillie

Yang, Yang https://orcid.org/0000-0001-6417-3654
Yuan, Chongli

Rochet, Jean-Christophe

Liu, Fei https://orcid.org/0000-0001-8601-4419
Xu, Ranjie https://orcid.org/0000-0001-9401-6430
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (R21NS140907)

U.S. Department of Health & Human Services | NIH | National Institute on Aging (U01AG088662)
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Text and Data Mining valid from 2025-05-02

Version of Record valid from 2025-05-02
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Article History

Received: 14 May 2024

Revised: 10 April 2025

Accepted: 24 April 2025

First Online: 2 May 2025

Competing interests

: The authors declare no competing interests.

: This study does not involve human participants.

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