Marchese, Maria https://orcid.org/0000-0002-0194-0702
Bernardi, Sara
Vivarelli, Rachele https://orcid.org/0009-0008-0450-2514
Doccini, Stefano
Santucci, Lorenzo https://orcid.org/0009-0001-2491-1322
Ogi, Asahi
Licitra, Rosario https://orcid.org/0000-0003-4879-6610
Zang, Jingjing
Soliymani, Rabah https://orcid.org/0000-0003-0184-3352
Mero, Serena
Neuhauss, Stephan CF
Ciarmoli, Lea
Signore, Giovanni
Lalowski, Maciej M. https://orcid.org/0000-0002-3683-4096
Santorelli, Filippo M. https://orcid.org/0000-0002-1359-9062
Funding for this research was provided by:
Ministero della Salute (SG-2018-12367839)
Ministero della Salute (RC 2024-2025)
Fondazione Telethon (GGP20011)
Fondazione Telethon (GSA23C003)
Fondazione Telethon (GGP20011)
Article History
Received: 11 November 2024
Revised: 14 April 2025
Accepted: 30 April 2025
First Online: 9 May 2025
Data sharing statement
: MS data presented in this study can be found in online repositories. The proteomics data were submitted to MassIVE (accession number MSV000095679) and ProteomeXchange (accession number PXD055114).
: The authors declare no competing interests.
: The generation of the mutant, using CRISPR/Cas9 technology, was performed with the ethical approval of the Italian Ministry of Health (approval n° 584/2019-PR), in accordance with the European Union’s Directive 2010/63/EU on the protection of animals used for scientific purposes, under the supervision of the University of Pisa Animal Care and Use Committee, and in compliance with the 3R principles.