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Authors
Zhang, Ziyan
Keyser, Cameron
Li, Yaxin
Rosolia, Breandan J. https://orcid.org/0009-0005-4574-7954
Porch, Morgan W.
Zhang, Wen
Su, Bin
Jiang, Peng
Zukin, R. Suzanne
Yan, Jingqi https://orcid.org/0000-0002-7024-6423
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS118378, NS116766)
Cleveland State University (Startup grant, Startup grant)
FRAXA Research Foundation (Research Grant)
U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (ES028960)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (MH092877)
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Article History
Received: 13 May 2024
Revised: 23 July 2025
Accepted: 27 August 2025
First Online: 10 September 2025
Competing interests
: The authors declare no conflict of interests.
: Human iPSC lines FX11-7 (WiCell WC005i-FX11-7), FX8-23 (WiCell WC005i-FX08-23), and C603 (WiCell WC008i-C603-4) were purchased from WiCell Research Institute (University of Wisconsin-Madison) under a material transfer agreement (MTA). These lines were originally derived under IRB-approved protocols at the University of Wisconsin–Madison by Dr. Anita Bhattacharyya as described in Stem Cells Dev. 2014;23(15):1777–1787. Informed consent was obtained from all donors at the time of tissue collection, and all donor information was de-identified prior to distribution. All animal procedures were approved by the Institutional Animal Care and Use Committees of Cleveland State University (protocol #21193) and Albert Einstein College of Medicine (protocol #00001012). All methods were performed in accordance with the relevant guidelines and regulations described in the approved protocols.
