Su, Xiao https://orcid.org/0000-0001-6408-8273
Zhang, Hanwen https://orcid.org/0000-0001-8490-918X
Hong, Yan
Yang, Qian https://orcid.org/0000-0003-4005-3580
Wang, Le
Le, Tiffany
Liu, Jiayi
Cheruvu, Lasya
Labour, Emily
Zhang, Siwei https://orcid.org/0000-0002-1646-063X
Mendez-Maldonado, Karla https://orcid.org/0000-0003-3762-0193
Kreimer, Anat
Song, Hongjun https://orcid.org/0000-0002-8720-5310
Ming, Guo-li https://orcid.org/0000-0002-2517-6075
Duan, Jubao https://orcid.org/0000-0002-7215-3220
Pang, Zhiping P. https://orcid.org/0000-0002-6183-1233
Funding for this research was provided by:
Robert Wood Johnson Foundation (74260)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH125528, R01MH125528)
Autism Science Foundation (ASF_23-004)
Funder: New Jersey Governor’s Council for Medical Research and Treatment of Autism Postdoctoral Fellowship Grant Reference Number:CAUT24DFP005
Article History
Received: 30 September 2024
Revised: 2 August 2025
Accepted: 5 September 2025
First Online: 17 September 2025
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. Human iPSC lines were obtained from RUCDR NIMH Stem Cell Center (). These iPSC lines were generated from cryopreserved lymphoblasts deposited by the Molecular Genetics of Schizophrenia (MGS) consortium, which had collected the biomaterials with informed consent as approved by the Endeavor Health (formerly NorthShore University HealthSystem) institutional review board (IRB). All animal work was performed without gender bias under the Institutional Animal Care and Use Committee (IACUC) protocol approved by the Rutgers University IACUC Committee.