Zhou, Hetong
Wang, Minmin
Qi, Shuangyu
Chen, Qianfeng
Lai, Jianbo https://orcid.org/0000-0002-8137-7701
Wu, Zhengping
Liu, Ruobing https://orcid.org/0009-0002-1411-903X
Wang, Liang https://orcid.org/0000-0001-9434-7571
Zhou, Hui https://orcid.org/0000-0001-8467-8676
Zhang, Shaomin
Hu, Shaohua https://orcid.org/0000-0003-0570-670X
Article History
Received: 10 June 2025
Revised: 28 August 2025
Accepted: 23 September 2025
First Online: 2 October 2025
Competing interests
: The authors declare no competing interests.
: This study was conducted in accordance with the Declaration of Helsinki and relevant institutional and national guidelines and regulations. The protocol was approved by the Ethics Committee of the First Affiliated Hospital of Zhejiang University School of Medicine (2022-019,2025B-0160). The trial was registered at ClinicalTrials.gov (NCT06516991). Written informed consent was obtained from each patient and their legal guardian prior to enrolment.