Uchiyama, Shunsuke https://orcid.org/0009-0000-7519-9534
Saito, Takeo https://orcid.org/0000-0003-3671-4585
Liu, Xiaoxi
Ishikawa, Yuki https://orcid.org/0000-0002-6514-8239
Hikino, Keiko https://orcid.org/0000-0002-4852-2401
Ikeda, Masashi
Genovese, Giulio https://orcid.org/0000-0003-3066-5575
Iwata, Nakao https://orcid.org/0000-0003-3189-6076
Terao, Chikashi https://orcid.org/0000-0002-6452-4095
Funding for this research was provided by:
Japan Agency for Medical Research and Development (21ek0109555, 21tm0424220, 21ck0106642, 23ek0410114, 23tm0424225)
Japan Agency for Medical Research and Development (JP21wm0425008, JP23tm0524001, JP21wm0525024, 21tm0424220, JP23dk0307123)
Japan Agency for Medical Research and Development (JP21wm0425008)
MEXT | Japan Society for the Promotion of Science (JP20H00462)
MEXT | Japan Society for the Promotion of Science (JP21H02854, 24K02381)
MEXT | Japan Society for the Promotion of Science (JP22H03003)
Article History
Received: 17 March 2025
Revised: 14 November 2025
Accepted: 2 December 2025
First Online: 15 January 2026
Competing interests
: S.U., T.S., X.L., Y.I., K.H., M.I., N.I. and C.T. have no conflicts of interest. G.G. declared competing interests, and patent application PCT/WO2019/079493 has been filed for the mosaic chromosomal alteration detection method used in this study.