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TrkB promotes the neuronal secretion of soluble Siglec-2 (CD22) to mitigate microglial activation and alleviate depression-like behaviors in male mice

Crossref DOI link: https://doi.org/10.1038/s41380-026-03575-7

Published Online: 2026-04-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shi, Xin https://orcid.org/0000-0003-4902-5498
Cai, Shi-zhong

Chai, Jin-long

Xu, Chen-yang https://orcid.org/0009-0004-0680-1658
Zhou, Bo-ya https://orcid.org/0009-0003-9804-174X
Liu, Han-qi https://orcid.org/0009-0005-7374-4339
Marshall, John https://orcid.org/0000-0002-9937-0268
Cao, Cong https://orcid.org/0000-0003-0824-3472
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Text and Data Mining valid from 2026-04-01

Version of Record valid from 2026-04-01
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Article History

Received: 27 July 2025

Revised: 3 March 2026

Accepted: 18 March 2026

First Online: 1 April 2026

Competing interests

: The authors declare no competing interests.

: No AI and AI-assisted technologies were used in the writing process.

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