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Authors
Kishi, Taro https://orcid.org/0000-0002-9237-2236
Sakuma, Kenji
Hatano, Masakazu
Hamanaka, Shun
Nishii, Yasufumi
Iwata, Nakao https://orcid.org/0000-0003-3189-6076
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Funding
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (23K06998)
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Article History
Received: 8 February 2025
Revised: 9 March 2026
Accepted: 30 March 2026
First Online: 6 April 2026
Competing interests
: All authors have no conflicts of interest to declare concerning this study. They also declare any potential competing interests that have arisen in the last 3 years. Dr. Kishi has received speaker’s honoraria from Daiichi Sankyo, Shionogi, Eisai, Janssen, Meiji, Otsuka, Sumitomo, Takeda, Mitsubishi-Tanabe, Kyowa, Boehringer Ingelheim, and Viatris and research grants from Eisai, JSPS KAKENHI (23K06998 and 25K10874), the Japan Agency for Medical Research and Development (JP22dk0307107, JP22wm0525024, 23dk0307117h0001, and 24dk0307129h0001, 256f0137005j0001, 266f0137005j0002, and 276f0137005j0003), and the Japanese Ministry of Health, Labour and Welfare (21GC1018). Dr. Sakuma has received speaker’s honoraria from Janssen, Kyowa, Meiji, Otsuka, Sumitomo, and Takeda and research grants from JSPS KAKENHI (19K17099 and 23K06998) and Japan Agency for Medical Research and Development (JP22dk0307107 and JP23dk0307122). Dr. Hatano received the speaker’s honoraria from Meiji and Sumitomo, and has received Grant-in-Aid for Early-Career Scientists (23K14827). Dr. Hamanaka has received speaker’s honoraria from Meiji, Otsuka, and Sumitomo. Dr. Nishii has received speaker’s honoraria from Meiji, Otsuka, and Sumitomo. Dr. Iwata has received speaker’s honoraria from Eisai, Janssen, Meiji, Otsuka, Sumitomo, Takeda, Mitsubishi-Tanabe, and Viatris and research grants from Daiichi Sankyo, Eisai, Meiji, Otsuka, Sumitomo, Takeda, Tanabe-Mitsubishi, Grant-in-Aid for Scientific Research (B)(22H03003), and Japan Agency for Medical Research and Development (JP22wm0425008).
: The current study includes a systematic review and meta-analysis based on secondary data from previously published, publicly available data. No new human or animal participants were recruited or studied directly by the authors. This study was performed in accordance with the relevant guidelines and regulations. All studies included in this systematic review and meta-analysis had received ethical approval from their respective institutional review boards, and informed consent was obtained from all participants in those original studies. Therefore, no additional ethical approval or informed consent was required for this study.
