Zhang, Jiashuo https://orcid.org/0000-0002-3786-211X
Zhang, Mengting
Zhao, Zhengyang
Xie, Min
Wei, Menghan
Liu, Siyi
Wu, Yulu
Tao, Shiwan https://orcid.org/0000-0002-7164-8758
Lv, Qiuyue https://orcid.org/0000-0003-2558-6530
Ma, Xiaoying
Huang, Yunqi https://orcid.org/0009-0003-6724-9724
Li, Mingli
Zou, Min
Wang, Qiang https://orcid.org/0000-0002-3849-1349
Funding for this research was provided by:
National Natural Science Foundation of China (82571712, 82171499)
Department of Science and Technology of Sichuan Province (2023YFS0030)
Postdoctor Research Fund of West China Hospital, Sichuan University
Postdoctor Research Fund of West China Hospital, Sichuan University
Article History
Received: 16 October 2025
Revised: 28 April 2026
Accepted: 27 May 2026
First Online: 2 June 2026
Competing interests
: The authors declare no competing interests.
: All experimental manipulations on rats in this study were approved by the Institutional Animal Care and Use Committee of the West China Hospital of Sichuan University (Approval Number: 20221206002) and followed the National Institutes of Health Guidelines for Animal Welfare. Regarding human data, we used de-identified, publicly available data from the ABCD study. ABCD study procedures were approved by multiple Institutional Review Boards across 21 sites, and all participating families provided phrase informed consent for data sharing and secondary research.