Stephan, Marius https://orcid.org/0000-0003-1889-3049
Papiol, Sergi
Zhang, Mingyue
Song, Jie https://orcid.org/0000-0002-7357-2136
Frommeyer, Samuel M.
Haupt, Helen
Jensen, Niels https://orcid.org/0000-0001-8171-3333
Kannaiyan, Nirmal https://orcid.org/0000-0002-7408-6842
Gupta, Rajinder
Schuler, Philipp
Pickelmann, Pia
Li, Ruofan
McCarthy, Michael https://orcid.org/0000-0001-6219-4945
Schulte, Eva C.
Landen, Mikael https://orcid.org/0000-0002-4496-6451
Falkai, Peter https://orcid.org/0000-0002-0284-2290
Scheuss, Volker https://orcid.org/0000-0002-0659-3228
Schulze, Thomas https://orcid.org/0000-0001-6624-2975
Zhang, Weiqi
Rossner, Moritz J. https://orcid.org/0000-0002-0667-3420
Funding for this research was provided by:
Bundesministerium für Bildung und Forschung (01EK2101D)
Department of Veterans Affairs | Veterans Affairs San Diego Healthcare System (BX003431)
Article History
Received: 2 April 2025
Revised: 1 July 2026
Accepted: 6 August 2026
First Online: 18 August 2026
Ethics
Competing interests: MMC has served in 2022 and 2023 on the scientific advisory board for the Alkermes Pharmaceuticals Pathways Young Investigator Award. NK is employee and MJR shareholder of Systasy Bioscience GmbH. None of the companies has contributed to the design and analyses of the study.
Ethics approval and consent to participate: Animal experiments were carried out in accordance with institutional guidelines and regulations approved by the Regierungspräsidium Oberbayern, ROB Munich, Germany under the license ROB-55.2-1-54-2532-179-2016. Human genetic analyses were performed only with published GWAS summary statistics as indicated.