Su, Qiao
Li, Meijuan
Qiu, Yuying
Sun, Xiaoxiao
Feng, Zhenning
Xu, Ying
Zhou, Boxuan
Funding for this research was provided by:
Tianjin Key Medical Discipline Construction Project (TJYXZDXK-3-015B) Natural Science Foundation of Tianjin Municipal Science and Technology Bureau
Article History
Received: 18 September 2025
Revised: 17 August 2026
Accepted: 2 September 2026
First Online: 16 September 2026
Ethics
Ethics declaration: All methods were performed in accordance with the relevant guidelines and regulations. This study analyzed publicly available GWAS summary statistics derived from previous studies, in which informed consent was obtained from all participants under the original institutional review board approvals. For the clinical cohort included in the exploratory analysis, the study protocol was reviewed and approved by the Ethics Committee of Tianjin Anding Hospital (No.2017-03, NCT07102069). Written informed consent was obtained from all patients prior to enrollment.
Competing interests: The authors declare no competing interests.