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Functional genomic profiling of schizophrenia-associated genes reveals key microglial regulators

Crossref DOI link: https://doi.org/10.1038/s41386-026-02406-1

Published Online: 2026-04-16

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Horng, Joy E.

McCrea, Liam T.

Batorsky, Rebecca E.

Bowen, Joshua J.

Boschian, Camilla

Song, Yoonjae

Perlis, Roy H. https://orcid.org/0000-0002-5862-6757
Sheridan, Steven D. https://orcid.org/0000-0003-1045-1158
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH120227)

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH131687)
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Article History

Received: 15 November 2025

Revised: 27 February 2026

Accepted: 31 March 2026

First Online: 16 April 2026

Competing interests

: Dr. Perlis has received personal fees from Circular Genomics, Genomind, Alkermes, and Atella for service as a scientific advisor, unrelated to the work described. He is a paid editor at JAMA + AI and an AI editor at JAMA Network-Open. The other authors have declared no competing financial interests in relation to the work described. A preprint of this study was submitted to bioRxiv ( ) during submission before review.

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