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Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2

Crossref DOI link: https://doi.org/10.1038/s41388-018-0589-1

Published Online: 2018-12-07

Published Print: 2019-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nishimura, Tatsunori

Nakata, Asuka

Chen, Xiaoxi

Nishi, Kurumi

Meguro-Horike, Makiko

Sasaki, Soichiro

Kita, Kenji

Horike, Shin-ichi

Saitoh, Kaori

Kato, Keiko

Igarashi, Kaori

Murayama, Takahiko

Kohno, Susumu

Takahashi, Chiaki

Mukaida, Naofumi http://orcid.org/0000-0002-4193-1851
Yano, Seiji

Soga, Tomoyoshi

Tojo, Arinobu http://orcid.org/0000-0001-9016-1948
Gotoh, Noriko
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Article History

Received: 14 December 2017

Revised: 21 August 2018

Accepted: 19 September 2018

First Online: 7 December 2018

Compliance with ethical standards

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: AT and NG obtained research funding from Daiichi Sankyo Co. ltd.