Song, Jiahang
Zhang, Junfeng
Shi, Yujing
Gao, Qing
Chen, Hui
Ding, Xiaofeng
Zhao, Minghui
Zhu, Caiqiang
Liang, Liang
Sun, Xinchen
Zhu, Yingyin
Wang, Wei
Li, Qing
Di, Xiaoke https://orcid.org/0000-0001-8680-4963
Funding for this research was provided by:
Natural Science Foundation of Jiangsu Province (BK20201080)
National Natural Science Foundation of China (82003228)
National Natural Science Foundation of China (82102831)
National Natural Science Foundation of China (82003235)
National Natural Science Foundation of China (82102830)
Court-level Natural Science Foundation Project of Jurong People’s Hospital
Court-level Natural Science Foundation Project of Jurong People’s Hospital
Article History
Received: 3 February 2024
Revised: 22 April 2024
Accepted: 23 April 2024
First Online: 14 May 2024
Change Date: 27 June 2025
Change Type: Update
Change Details: The original online version of this article was revised: Following the publication of this article, the authors noted that the KYSE410 USP2 image in Figure 5E was mistakenly duplicated with the KYSE150 shNC image in Figure 5E. Additionally, the KYSE150 image 2 in Figure S8G was mistakenly duplicated with the KYSE410 image 4 in Figure 4C. The authors also noted an error in the textual description in the Abstract section. The corrected version is as follows: “Moreover, USP2 silencing decreased the iron ion concentration and lipid peroxidation accumulation as well as suppressed ferroptosis, while upregulating USP2 promoted ferroptotic cell death in ESCC cells.” Furthermore, figure legends for tumor weight data (Figure 8H and Figure S12C) have been revised to clarify that the error bars represent the means with 95% confidence intervals, rather than standard deviations (SD) as previously stated. The corrected versions are as follows:
Change Details: Fig. 8 USP2 regulates ESCC tumorigenesis in vivo
Change Details: (H) Representative images of tumors and quantification of tumor weights in nude mice bearing ESCC cells in indicated groups (n = 3). Data are presented as the means with 95% confidence intervals from three independent experiments.
Change Details: Fig. S12 USP2 regulates ESCC tumorigenesis in vivo
Change Details: (C) Representative images of tumors and quantification of tumor weights in nude mice bearing ESCC cells in indicated groups (n = 3). Data are presented as the means with 95% confidence intervals from three independent experiments.
Change Details: The authors confirm this correction does not affect the conclusions of the paper and apologize for any inconvenience caused. The original article has been corrected.
Change Date: 27 June 2025
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s41388-025-03443-8
Competing interests
: The authors declare no competing interests.