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Spermine oxidase promotes Helicobacter pylori-mediated gastric carcinogenesis through acrolein production

Crossref DOI link: https://doi.org/10.1038/s41388-024-03218-7

Published Online: 2024-11-10

Published Print: 2025-02-18

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

McNamara, Kara M.

Sierra, Johanna C.

Latour, Yvonne L.

Hawkins, Caroline V.

Asim, Mohammad

Williams, Kamery J.

Barry, Daniel P. https://orcid.org/0000-0002-3972-3914
Allaman, Margaret M. https://orcid.org/0000-0002-2803-1365
Zagol-Ikapitte, Irene

Luis, Paula B.

Schneider, Claus

Delgado, Alberto G.

Piazuelo, M. Blanca

Tyree, Regina N.

Carson, Kate S.

Choksi, Yash A. https://orcid.org/0000-0003-1717-4472
Coburn, Lori A. https://orcid.org/0000-0003-3249-9806
Gobert, Alain P. https://orcid.org/0000-0001-7535-539X
Wilson, Keith T. https://orcid.org/0000-0003-4421-1830
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Cancer Institute (R41CA257262)

U.S. Department of Health & Human Services | NIH | National Cancer Institute (P01CA116087)

U.S. Department of Health & Human Services | NIH | National Cancer Institute (P01CA028842)

U.S. Department of Health & Human Services | NIH | National Cancer Institute (T32CA009592)

U.S. Department of Health & Human Services | NIH | National Cancer Institute (F31CA278330)

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (R21AI142042)

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (T32AI138932)

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (R01DK128200)

U.S. Department of Veterans Affairs (I01BX001453)

U.S. Department of Veterans Affairs (I01CX002171)

U.S. Department of Veterans Affairs (I01CX002473)

U.S. Department of Veterans Affairs (IK2BX004748)

U.S. Department of Veterans Affairs (I01BX004366)

U.S. Department of Defense (W81XWH-18-1-0301)

U.S. Department of Defense (W81XWH-21-1-0617)
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Text and Data Mining valid from 2024-11-10

Version of Record valid from 2024-11-10
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Article History

Received: 3 July 2024

Revised: 29 October 2024

Accepted: 1 November 2024

First Online: 10 November 2024

Competing interests

: APG and KTW are named inventors on a US patent, Compounds and Methods for Scavenging Dicarbonyl Electrophiles (Patent # 11696903), for use of electrophile scavengers, which is assigned to Vanderbilt University and The United States Government as represented by the Department of Veterans Affairs. In addition, APG and KTW receive royalty payments from a licensing agreement between Vanderbilt University and MTI Biotech for the future use of electrophile scavengers. All other authors have declared that no conflict of interest exists.

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