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EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair

Published Online: 2024-11-19

Published Print: 2025-02-24

Authors

Yu, Jianzhong

Han, Jichang https://orcid.org/0000-0001-6677-9705
Yu, Meng

Rui, Huanwen

Sun, An https://orcid.org/0009-0003-2386-029X
Li, Hao https://orcid.org/0000-0001-7755-1749
Funding

Funding for this research was provided by:

Cyrus Tang Foundation (ZSBK0070)

National Natural Science Foundation of China (82103123)

China Postdoctoral Science Foundation (2021M703208)
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Text and Data Mining valid from 2024-11-19

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Article History

Received: 20 August 2024

Revised: 7 November 2024

Accepted: 11 November 2024

First Online: 19 November 2024

Competing interests

: The authors declare no competing interests.

: MB tissue specimens were obtained from the Children’s Hospital of Fudan University after approval by the ethics review board of the hospital. All patients were informed, and consent was obtained. All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of the Children’s Hospital of Fudan University.

: The authors consent to publish the paper.

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