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Authors
Zhao, Xuejiao
Lai, Huiling
Li, Guannan
Qin, Yu
Chen, Ruqi
Labrie, Marilyne
Stommel, Jayne M.
Mills, Gordon B. https://orcid.org/0000-0002-0144-9614
Ma, Ding https://orcid.org/0009-0008-2360-2035
Gao, Qinglei
Fang, Yong https://orcid.org/0000-0003-3412-8208
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (81572565)
National Natural Science Foundation of China (81874109)
National Natural Science Foundation of China (82272707)
National Natural Science Foundation of China (82072894)
National Natural Science Foundation of China (81602291)
National Natural Science Foundation of China (82303279)
National Natural Science Foundation of China (82303038)
China Postdoctoral Science Foundation
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Article History
Received: 15 November 2024
Revised: 14 February 2025
Accepted: 11 March 2025
First Online: 25 March 2025
Competing interests
: GM is a SAB member/Consultant for Amphista, Astex, AstraZeneca, Biodyne, BlueDot, Chrysallis Biotechnology, Ellipses Pharma, GSK, ImmunoMET, Infinity, Ionis, Leapfrog Bio, Lilly, Medacorp, Nanostring, Neophore, Nerviano, Nuvectis, Pangea, PDX Pharmaceuticals, Qureator, Roche, Rybodyne, Signalchem Lifesciences, Tarveda, Turbine, Zentalis Pharmaceuticals has Stock/Options/Financial contributions from Bluedot, Biodyne, Catena Pharmaceuticals, ImmunoMet, Nuvectis, RyboDyne, SignalChem, Tarveda, Turbine has Licensed Technology HRD assay to Myriad Genetics, DSP patents with Nanostring and has sponsored or collaborative research with AstraZeneca, Zentalis, and Nanostring. G.M. has received support that is not directly related to this manuscript. The authors declare no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or conflict with the subject matter or materials discussed in this manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
: All methods were conducted in strict accordance with relevant guidelines and regulations. Mouse experiments were performed under a protocol approved by the Ethics Committee of Tongji Hospital, Tongji Medical College. Patient samples were sourced from the Clinical Database and Biobank of Patients with Gynecologic Neoplasm, registered under ClinicalTrials.gov Identifier NCT01267851. Ethical approval details can be accessed at .
