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DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells

Crossref DOI link: https://doi.org/10.1038/s41388-025-03409-w

Published Online: 2025-04-15

Published Print: 2025-07-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wu, Wenjing

Wu, Weijun

Xie, Xiaojuan

Li, Jing

Gao, Yuan

Xie, Limin

Zhong, Caixia

Xiao, Jianhong

Cai, Manbo

Yin, Dong https://orcid.org/0000-0002-1878-4849
Hu, Kaishun https://orcid.org/0000-0003-2157-6239
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82373150, 82172636, 82373023)
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Text and Data Mining valid from 2025-04-15

Version of Record valid from 2025-04-15
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Article History

Received: 17 July 2024

Revised: 2 April 2025

Accepted: 7 April 2025

First Online: 15 April 2025

Competing interests

: The authors declare no competing interests.

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