Cong, Bojie
Thakur, Teena
Uribe, Alejandro Huerta
Stamou, Evangelia
Gopinath, Sindhura
Sansom, Owen
Maddocks, Oliver https://orcid.org/0000-0002-5551-9091
Cagan, Ross https://orcid.org/0000-0001-5297-450X
Funding for this research was provided by:
Foundation for the National Institutes of Health (R01CA258736)
Royal Society (Wolfson Fellowship)
Article History
Received: 13 August 2024
Revised: 29 April 2025
Accepted: 9 June 2025
First Online: 10 July 2025
Competing interests
: The authors declare no competing interests.
: All procedures conformed to institutional, national, and international regulations. Work with Drosophila , which is exempt from the UK Animals (Scientific Procedures) Act, was nevertheless reviewed under the University of Glasgow Drosophila guidelines. Derivation of Vil-CreERT2; Apc fl/fl ; Kras G12D/+ ; Trp53 fl/fl mouse intestinal organoids was performed in accordance with Home Office License: PPL 60/4492, authorised by the University of Glasgow Animal Welfare and Ethical Review Body, and conducted under the UK Animals (Scientific Procedures) Act.