Funding for this research was provided by:
Science and Technology Fund of Tianjin Municipal Health Commission
Article History
Received: 11 November 2024
Revised: 3 July 2025
Accepted: 4 August 2025
First Online: 12 August 2025
Competing interests
: The authors declare no competing interests.
: This study did not involve human participants, human tissue, or live vertebrate animals. All analyses were conducted using publicly available datasets and computational modeling techniques. Therefore, ethical approval from our institutional ethics committee and informed consent were not required for this research.