Cheng, Xiang
Wang, Mengmeng
Li, Wei
Tian, Bingzhang
Zhang, Jing
Zhang, Chen
Liu, Pian https://orcid.org/0000-0001-5780-3902
Funding for this research was provided by:
National Natural Science Foundation of China (82072945, 81772800, 82302971)
Natural Science Foundation of Hubei Province (2023AFB1020, 2023AFB190, 2024AFB667)
Natural Science Foundation of Hunan Province (2023JJ60453)
Hunan Provincial Health Commission Scientific Research Program
Article History
Received: 26 April 2025
Revised: 6 August 2025
Accepted: 2 September 2025
First Online: 30 September 2025
Competing interests
: The authors declare no competing interests.
: The study was conducted in accordance with the principles of the Declaration of Helsinki principles. It was approved by the Animal Use and Care Committees at the Second Xiangya hospital, Central South University (approval number 20241070). All subjects have written informed consent.