Ren, Yuqing
Ming, Ruijie
Zuo, Anning
Liu, Shutong
Ba, Yuhao
Zhang, Yuyuan
Chen, Yukang
Pan, Teng
Luo, Peng
Cheng, Quan https://orcid.org/0000-0003-2401-5349
Deng, Jinhai
Yue, Yi
Xu, Hui
Weng, Siyuan
Han, Xinwei https://orcid.org/0000-0003-4407-4864
Zhou, Dongdong
Liu, Zaoqu https://orcid.org/0000-0002-0452-742X
Funding for this research was provided by:
Science and Technology Department of Henan Province (221100310100)
Article History
Received: 12 March 2025
Revised: 20 August 2025
Accepted: 3 September 2025
First Online: 19 September 2025
Competing interests
: The authors declare no competing interests.
: All human tissue samples were obtained with written informed consent from each patient and approved by the Ethics Committee (Approval Nos. HLugA120PG01: 2020-0930; HLugA030PG04-2: 2021-0215; HLugA180Su07: 2022-0401). All animal experiments were approved by the Institutional Animal Care and Use Committee of Zhengzhou University (Ethical Approval No. 2019-KY-383) and conducted in strict accordance with the National Institutes of Health (NIH) guidelines for animal care and use.