Huang, Hongbiao https://orcid.org/0000-0002-9873-0559
Xiang, Yujie https://orcid.org/0009-0003-1441-3164
Deng, Yuanfei https://orcid.org/0000-0002-8326-2713
Liu, Qing https://orcid.org/0000-0002-4101-3495
Cai, Gengxi https://orcid.org/0000-0003-0575-4314
Lei, Qiucheng https://orcid.org/0009-0007-8595-6624
Sun, Wenshuang https://orcid.org/0000-0003-2692-6648
Yin, Shusha https://orcid.org/0009-0002-9780-9027
Li, Yuting https://orcid.org/0009-0001-7333-0372
Peng, E-ying https://orcid.org/0009-0008-2067-1510
Yao, Yu https://orcid.org/0009-0002-3343-3235
Yao, Leyi https://orcid.org/0009-0009-1987-7770
Xu, Dacai https://orcid.org/0000-0002-2566-7077
Shao, Zhenlong https://orcid.org/0000-0001-8039-8706
Liao, Yuning https://orcid.org/0009-0003-0767-3937
Article History
Received: 26 February 2025
Revised: 19 September 2025
Accepted: 23 October 2025
First Online: 3 November 2025
Competing interests
: The authors have declared that no conflicts of interest exist.
: For human samples, all procedures were approved by the Medical Ethics Committee of the First People’s Hospital of Foshan (Ethics number: 2024, NO.115), and informed consent was obtained from all subjects. All animal studies involved in this research were approved by the institutional animal care and use committees of Guangdong Zhiyuan Biopharmaceutical Technology Co., Ltd (IAEC-2024100901), and were performed in accordance with ARRIVE guidelines. Details of this study were described in Supplementary data/Supplementary materials and methods.