Wang, Haoran https://orcid.org/0009-0005-7714-6977
Ge, Lichen https://orcid.org/0000-0002-9440-5185
Li, Jianing
Zhong, Ke https://orcid.org/0009-0004-5519-628X
Li, Shanzhi
Ma, Ningjing
Tao, Lijun
Zhou, Jiawang
Wang, Zhaotong
Chang, Xing
Lu, Yunqing
Rui, Yalan
Xie, Guoyou
Yang, Weifeng
Xu, Zuanzong
Saad, Abdulaziz Ahmed A.
Wang, Xiansong
Chen, Zhuojia https://orcid.org/0000-0003-0343-3795
Li, Wanglin
Yi, Cheng https://orcid.org/0009-0009-0858-7030
Wang, Hongsheng https://orcid.org/0000-0002-0054-4820
Zhang, Kun https://orcid.org/0000-0001-5891-0400
Funding for this research was provided by:
National Natural Science Foundation of China (82472761, 82173833, and 82272658)
Article History
Received: 9 May 2025
Revised: 14 November 2025
Accepted: 2 December 2025
First Online: 27 December 2025
Competing interests
: The authors declare no competing interests.
: This study was conducted with approval from the Medical Ethics Committee of Huadu District People’s Hospital, Guangzhou (Approval No. 2025158) and informed consent from all patients, in compliance with the Declaration of Helsinki. Animal experimental protocols were reviewed and approved by the Institutional Animal Care and Use Committee of Sun Yat-sen University (Approval Nos. SYSU-IACUC-2023-001865, SYSU-IACUC-2024-001583).