Huang, Minghan
Xie, Wenqing
Wu, Meihua
Ou, Zhimei
Li, Caibin
Ji, Shuhui
Liu, Wanjun
Zhi, Min
Chen, Daici https://orcid.org/0000-0002-8872-0592
Funding for this research was provided by:
National Natural Science Foundation of China (31970703)
Natural Science Foundation of Guangdong Province (2025A1515010593)
Natural Science Foundation of Guangdong Province (2022A1515012472)
Article History
Received: 25 July 2025
Revised: 14 November 2025
Accepted: 2 December 2025
First Online: 17 December 2025
Competing interests
: This work was financially supported by the Natural Science Foundation of China (Grant No. 31970703), Natural Science Foundation of Guangdong Province (Grant No. 2025A1515010593 and 2022A1515012472). The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
: All methods were performed in accordance with the relevant guidelines and regulations. The animal experiments were approved by the Laboratory Animal Center of SYSU-SAH (approval no. IACUC-2023122702), and tumor sizes were within the requirements of the animal center (<2 cm). Our study involving human specimens was approved by the Institutional Ethics Committee of SYSU-SAH (approval no. 2022ZSLYEC-469). All specimens in the SYSU-SAH biobank were collected and deposited after obtaining written informed consent from participants. This was a retrospective analysis of anonymized data, as the authors had no access to identifiable personal information during the analysis. Therefore, the requirement for informed consent was waived to this study by the ethics committee in accordance with applicable guidelines and regulations.