Hayashida, Hiroki https://orcid.org/0009-0003-6324-7916
Masamoto, Yosuke https://orcid.org/0000-0002-8168-6459
Oyama, Takashi
Hino, Toshiya
Morita, Ken
Fujiki, Katsunori
Nakato, Ryuichiro https://orcid.org/0000-0003-3019-5817
Shirahige, Katsuhiko
Kurokawa, Mineo https://orcid.org/0000-0002-4034-2422
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP21H04805)
MEXT | Japan Society for the Promotion of Science (JP22KJ0806)
MEXT | Japan Society for the Promotion of Science (JP24K19194)
MEXT | Japan Society for the Promotion of Science (JP20H03708)
MEXT | Japan Society for the Promotion of Science (JP22K16299)
Japan Agency for Medical Research and Development (JP23ama121020)
Article History
Received: 5 September 2025
Revised: 31 January 2026
Accepted: 5 March 2026
First Online: 25 April 2026
Competing interests
: Y.M. and M.K. have received honoraria from Bristol Myers Squibb. The other authors declare no competing financial interests.
: All experiments have been performed in accordance with the relevant guidelines and regulations. This research article does not include any studies with live vertebrates or humans.